Metabolism of propanoate begins with its conversion to propionyl coenzyme A (propionyl-CoA), the usual first step in the metabolism of carboxylic acids. Since propanoic acid has three carbons, propionyl-CoA can directly enter neither beta oxidation nor the citric acid cycles. In most vertebrates, propionyl-CoA is carboxylated to D-methylmalonyl-CoA, which is isomerised to L-methylmalonyl-CoA. A vitamin B 12 -dependent enzyme catalyzes rearrangement of L-methylmalonyl-CoA to succinyl-CoA, which is an intermediate of the citric acid cycle and can be readily incorporated there.
In most cases a good Winstrol cycle will run for approximately 6-8 weeks at a dosing of 50mg every day. Some will find 50mg every other day to be all they need but as this anabolic steroid has a very short half-life, especially in tablet form daily administration is generally best. 50mg per day appears to be perfect for most any man regardless of his level of experience and we do not recommend going beyond the 8 week mark as this steroid is rather liver toxic. Winstrol is one of the more hepatic anabolic steroids we will ever use but thankfully if used responsibly the liver will return to normal values very quickly after use has been discontinued. The only exception we might make regarding the dose of a Winstrol cycle is for the competitive bodybuilder towards the very end of his contest prep cycle. Many bodybuilders find 100mg per day the last 10-14 days before a show to be very useful in-terms of really hardening them up before they step on stage; however, 14 days is the maximum recommended duration for such a dose due to the toxicity of this steroid.
Anabolic steroids differ in their characteristics, which means there are steroids that are only suitable for specific uses. For instance, Trenbolone is not recommended for bulking but it is an outstanding fat burner. This makes it perfect for a lean mass cycle or a cutting cycle. Always take the side effects of a particular compound into consideration whenever you plan a stack. Do not combine anabolic steroids that show similar side effects. For example, never combine Anapolon and Dianabol because they are already quite toxic and if you combine them, the toxicity will increase exponentially and cause serious damage to your body.