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The human brain is primarily composed of neurons , glial cells , neural stem cells , and blood vessels . Types of neuron include interneurons , pyramidal cells including Betz cells , motor neurons ( upper and lower motor neurons ), and cerebellar Purkinje cells . Betz cells are the largest cells (by size of cell body) in the nervous system. [34] The adult human brain is estimated to contain 86±8 billion neurons, with a roughly equal number (85±10 billion) of non-neuronal cells. [35] Out of these neurons, 16 billion (19%) are located in the cerebral cortex, and 69 billion (80%) are in the cerebellum. [4] [35]

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