Clenbuterol is a bronchodilator and is the popular name for Clenbuterol Hydrochloride. It was originally created to treat chronic asthma and other similar conditions. However, what makes it appealing to athletes and bodybuilders is its efficacy in burning fat. It is able to increase metabolic activity and burn body fat very effectively as it stimulates the Beta-2 receptors. This also increases cellular heat as the heat production of the cells is increased, which in turn increases the overall body temperature and the rate in which fat is burnt. Clen has also been known to suppress the appetite among some users.
People who want to buy Clenbuterol pills must remember that it is not a steroid in any way although it mimics some steroidal properties. In fact, Clen mimics the effects of adrenaline and noradrenaline in the human body. Users who are not comfortable with other thermogenic like caffeine and ephedrine should not use Clenbuterol tablets. Recommended dosage for good fat burning and noticeable muscle gain is 100-140mcg per day for men, which amounts to 5-7 tablets daily. For women, the recommended dosage is 80-100mcg per day, which is 4-5 tablets.
There are two ways to use Clen. The 2 weeks on and 2 weeks off is the most popular way to use this drug. Here, users start off with a low dose and increase the dosage every 2 to 3 days. Once the body gets accustomed to the drug, users discontinue it for two weeks. After two weeks, users begin taking the drug at a level close to where they stopped last time. The other way is the steady use where users start with a low dose and gradually increase the dosage.
Clenbuterol which improves metabolic activity and cardiovascular activity greatly. It also increases lean muscle mass quite effectively. This muscle building effect is brought about by increased protein synthesis in the body. However, due to its powerful stimulating effect side effects like insomnia and experiencing a very jittery feeling is common when large doses are taken. It is also known to cause cramping among some users. An extreme side effect of Clenbuterol is cardiac hypertrophy where the ventricles of the heart become larger. However, this occurs only when the doses are large. As with other fat burning remedies, Clen should not be used for long periods of time.
A 2016 phase 1–2 prospective study orally administered 800 mg per day to 27 patients with telomere diseases. The primary efficacy endpoint was a 20% reduction in the annual rate of telomere attrition measured. Toxic effects formed the primary safety endpoint. The study was halted early, after telomere attrition was reduced in all 12 patients who could be evaluated. 12 of 27 patients achieved the primary efficacy end point, 11 of whom increased telomere length at 24 months. Hematologic responses (secondary efficacy endpoint) occurred in 10 of 12 patients who could be evaluated at 24 months. Elevated liver-enzyme levels and muscle cramps (known adverse effects) of grade 2 or less occurred in 41% and 33% of the patients, respectively.